Approximately 1 in 5 adults in the US had a sexually transmitted infection in 2018. Khalil Ghanem, MD, PhD, of Johns Hopkins University joins JAMA Deputy Editor Mary McDermott, MD, to discuss the newest recommendations regarding the diagnosis and treatment of sexually transmitted infections, including gonorrhea, chlamydia, syphilis, Mycoplasma genitalium, and trichomoniasis.
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Pulmonary nodules are commonly found on lung imaging studies. Evaluation and management depends on the size and other characteristics of pulmonary nodules and patient risk factors for malignancy. JAMA Associate Editor Kristin Walter, MD, MS, discusses the recent JAMA article “Evaluating the Patient With a Pulmonary Nodule: A Review” with one of the authors, Peter Mazzone, MD, MPH, a pulmonologist and director of the Lung Cancer Program for the Respiratory Institute at the Cleveland Clinic.
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The last few years have seen a tremendous increase in the conduct of platform clinical trials, a type of randomized clinical trial that can simultaneously evaluate the effects of multiple interventions, often in combination, with the available treatments changing over time as more is learned about their effectiveness. Jay J.H. Park, PhD, and Edward J. Mills, PhD, from the University of British Columbia and McMaster University, respectively, join JAMA Statistical Editor Roger J. Lewis, MD, PhD, to discuss how clinicians should evaluate the results of platform clinical trials when considering incorporating the results into their clinical practice.
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