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JAMA Clinical Reviews

Interviews with expert clinicians and researchers about topics relevant to clinical practice and patient care, including updates in management of common conditions from JAMA, the Journal of the American Medical Association.
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Now displaying: 2022

In-depth interviews about current ideas and innovation in medicine, science, and clinical practice.

Dec 27, 2022

Anxiety disorders affect approximately a third of adults during their lifetime in the US and are associated with significant distress and impairment. JAMA Deputy Editor Mary M. McDermott, MD, discusses diagnosis and treatment of anxiety disorders with Naomi M. Simon, MD, MSc, professor of the Department of Psychiatry at NYU Grossman School of Medicine.

Related Article(s):

Anxiety Disorders

Dec 6, 2022

Bacterial meningitis is a worldwide health problem causing approximately 300 000 deaths annually. In this podcast, JAMA Fishbein Fellow Revital Marcus, MD, speaks with Rodrigo Hasbun, MD, MPH, infectious disease specialist and professor of medicine at the University of Texas Health Science Center in Houston, about the epidemiology, diagnosis, and treatment of bacterial meningitis.

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Dec 1, 2022

Rajesh T. Gandhi, MD, director of Harvard University’s Center for AIDS Research, talks about recent advances in the treatment and prevention of HIV and discusses HIV in the context of COVID-19 and monkeypox infections. Hosted by JAMA Deputy Editor and Editorial Director for Equity Preeti Malani, MD, MSJ.

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Nov 15, 2022

Phenome-wide association studies use large data sets to search for phenotypes associated with specific single-nucleotide variants, investigating whether specific genetic variations may be associated with multiple conditions and traits. In this podcast, JAMA Fishbein Fellow Revital Marcus, MD, discusses phenome-wide association studies with Dan M. Roden, MD, professor of medicine, pharmacology, and biomedical informatics at Vanderbilt University Medical Center, and Joshua C. Denny, MD, MS, chief executive officer of the National Institutes of Health's All of Us Research Program.

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Nov 8, 2022

JAMA Interim Executive Editor Gregory Curfman, MD, interviews Robert M. Carey, MD, University of Virginia, about his review article on treatment of hypertension in the November 8, 2022, issue of JAMA. Their discussion addresses the clinical consequences of hypertension, as well as nonpharmacological and pharmacological approaches to management, including patients with resistant hypertension.

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Nov 1, 2022

Michele Bratcher Goodwin, JD (Center for Biotechnology and Global Health Policy, University of California, Irvine), Molly Meegan, JD (American College of Obstetricians and Gynecologists), and Lisa Harris, MD, PhD (University of Michigan) discuss how new abortion bans in the US are creating serious legal and ethical dilemmas for clinicians. Hosted by JAMA Legal and Global Health Correspondent Lawrence O. Gostin, JD (Georgetown University).

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Conflict of Interest Disclosures:

Lawrence O. Gostin, JD, is the Legal and Global Health Correspondent for JAMA and Faculty Director of the O’Neill Institute for National and Global Health Law at Georgetown University.  No other disclosures were reported.

Michele Bratcher Goodwin, JD, LLM, SJD is Director of the Center for Biotechnology and Global Health Policy at University of California, Irvine.  No other disclosures were reported.  Lisa Harris, MD, PhD, is the F. Wallace and Janet Jeffries Collegiate Professor of Reproductive Health, and Professor and Associate Chair in the Department of Obstetrics and Gynecology at University of Michigan. She is also a Professor in the Department of Women’s Studies.  No other disclosures reported.  Molly Meegan is the Chief Legal Officer and General Counsel for the American College of Obstetricians and Gynecologists (ACOG).  No other disclosures reported.

Nov 1, 2022

An estimated 45% of accredited US obstetrics and gynecology residency programs are located in states that currently ban or severely restrict abortions. JAMA Associate Editor Linda Brubaker, MD, and JAMA Internal Medicine Deputy Editor Deborah Grady, MD, speak with medical students, program directors, and other specialists in the ob-gyn training community about new restrictions and their effects on ob-gyn education in the US.

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Conflict of Interest Disclosures:

Hannah Nguyen reported that she held leadership positions on Boston University’s School of Medicine chapters of SPA-1 and DREAM. Margaux Zimmerman reported that she held leadership positions on Boston University’s, School of Medicine chapters of ACOG and DREAM. Dr Gariepy reported that she was the Yale Complex Family Planning fellowship director from 2018 to March 2022, for which she received salary support from her institution; taught undergraduate and medical students, ob-gyn residents, and Complex Family Planning fellows; and is a research mentor for Complex Family Planning fellows who received research grants from the Society of Family Planning Research Fund. Dr Gariepy also reported leadership positions on the board of directors for the Society of Family Planning and the Complex Family Planning Fellowship Council and membership with Physicians for Reproductive Health, the National Abortion Federation, and the Society of Family Planning. Dr Steinauer is a member of the Society of Family Planning. Dr Loder reported that she serves as a principal investigator for contraceptive clinical trials for Merck and Sebela Pharmaceuticals Inc, consults for American Medical Students Association, and serves as program director for Complex Family Planning Fellowship, University of Michigan, Michigan Medicine. No other disclosures were reported.

Nov 1, 2022

JAMA Associate Editor Linda Brubaker, MD, MS, discusses medication abortion as an alternative to a procedural abortion to terminate a pregnancy in an interview with Stephanie Teal, MD, MPH, University Hospitals Cleveland Medical Center, and Rebecca Cohen, MD, OB/GYN, University of Colorado.

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Conflict of Interest Disclosures:
Dr Cohen serves as an unpaid board member for Cobalt, a reproductive rights advocacy group. No other disclosures were reported.

Oct 25, 2022

Hypercalcemia affects approximately 1% of the population. Its presence typically indicates an underlying disorder and requires diagnostic evaluation. In this podcast, JAMA Associate Editor Anne Cappola, MD, ScM, interviews Elizabeth Shane, MD, an endocrinologist and professor of medicine at Columbia University Medical Center, about the clinical approach to diagnosing and managing hypercalcemia.

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Oct 4, 2022

In the US, pulmonary embolism (PE) affects approximately 370 000 patients annually and is estimated to cause 60 000 to 100 000 deaths per year. In this podcast, JAMA Senior Editor Kristin Walter, MD, MS, discusses the clinical presentation, diagnostic strategies, and treatment of PE with Yonathan Freund, MD, PhD, professor of emergency medicine at Sorbonne University in Paris, France.

Related Article(s):

Sep 30, 2022

Hyponatremia affects approximately 5% of adults and approximately 35% of hospitalized patients. Even mild hyponatremia can be associated with cognitive impairment; in hospitalized patients, hyponatremia is associated with longer hospital stays and increased mortality. In this podcast, JAMA Deputy Editor Mary M. McDermott, MD, interviews Nicolaos E. Madias, MD, a nephrologist and professor of medicine at Tufts University School of Medicine, about the clinical approach to diagnosing hyponatremia and management of both acute and chronic hyponatremia.

Related Content:

Diagnosis and Management of Hyponatremia

Sep 6, 2022

Myelodysplastic neoplasms, or myelodysplastic syndromes, are diagnosed in approximately 4 of 100 000 people each year in the US and are associated with a 5-year survival rate of approximately 37%. In this JAMA podcast and author interview, JAMA Deputy Editor Mary M. McDermott, MD, discusses the diagnosis and treatment of myelodysplastic syndromes with Mikkael A. Sekeres, MD, MS, chief of hematology and professor of medicine of the Sylvester Comprehensive Cancer Center at the University of Miami Miller School of Medicine.

Related Content:

Diagnosis and Treatment of Myelodysplastic Syndromes

Aug 26, 2022

JAMA Associate Editor Preeti Malani, MD, MSJ, discusses testing, treatment, and prevention of monkeypox infection and the current state of the 2022 outbreak with Carlos del Rio, MD, from Emory University’s Department of Medicine. Recorded August 19, 2022.

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Aug 26, 2022

JAMA Associate Editor Preeti Malani, MD, MSJ, discusses the transmission, diagnosis, and treatment of monkeypox and the 2022 outbreak with Jeannette Guarner, MD, and Carlos del Rio, MD, both of the Division of Infectious Diseases at Emory University’s School of Medicine. Recorded July 11, 2022.

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Aug 16, 2022

Barrett esophagus affects approximately 5% of people in the US and approximately 1% worldwide; it's associated with an increased risk of esophageal adenocarcinoma. JAMA Deputy Editor Mary M. McDermott, MD, interviews Prateek Sharma, MD, a gastroenterologist and professor of medicine at University of Kansas School of Medicine, about the diagnosis, surveillance, and available therapy for patients affected by Barrett esophagus.

Related Article(s):

Aug 2, 2022

Malaria is diagnosed in approximately 2000 people in the US each year. Delay in diagnosis or inappropriate treatment of malaria is associated with increased mortality. In this podcast, JAMA Deputy Editor Mary M. McDermott, MD, interviews Johanna P. Daily, MD, MS, Albert Einstein College of Medicine, an infectious disease expert and scientist studying malaria, on the diagnosis, treatment, and prevention of malaria in the US.

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Jul 14, 2022

Pregnancy inherently increases the risk of death, but certain conditions during pregnancy are considered life-threatening. In this podcast, JAMA Associate Editor Linda Brubaker, MD, discusses with maternal-fetal medicine specialists William A. Grobman, MD, The Ohio State University, and Cynthia Gyamfi-Bannerman, MD, MS, University of California, San Diego, the categories of life-threatening conditions, as well as the racial and ethnic disparities associated with pregnancy-associated mortality.

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Jul 5, 2022

In July 2022, Kirsten Bibbins-Domingo, PhD, MD, MAS, took on a new role as the 17th editor in chief of JAMA and the JAMA Network. In conversation with Nobel laureate Harold Varmus, MD, Bibbins-Domingo discusses her research background, approaches to leadership in health care, and the critical role that journals play in communication about public health and science.

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Jul 5, 2022

In the US, approximately 100 000 people have sickle cell disease, a chronic condition characterized by hemolytic anemia, acute and chronic pain, increased rates of stroke and nephropathy, and an average lifespan that is 20 years less than that of the general population. In this podcast, JAMA Deputy Editor Mary McDermott, MD, interviews review article author Patricia Kavanaugh, MD, on the diagnosis and management of sickle cell disease. Discussion includes a summary of 3 new therapies for sickle cell disease and some of the social, structural, and cultural challenges encountered by patients with sickle cell disease.

Related Content:

Sickle Cell Disease

Jun 28, 2022

Carpal tunnel syndrome and trigger finger are common hand conditions in primary care practice that are associated with pain and disability. In this JAMA podcast, JAMA Deputy Editor Mary M. McDermott, MD, and Kelly Currie, MD, assistant professor in the Washington University Division of Plastic & Reconstructive Surgery in St Louis, Missouri, discuss the diagnosis and treatment of these conditions and other hand problems that are commonly encountered in primary care.

Related Content:

Common Hand Conditions

Patient Information: Carpal Tunnel Syndrome

May 17, 2022

JAMA Associate Editor Ethan Basch, MD, and Melanie Calvert, PhD, from the University of Birmingham, UK, discuss barriers to and strategies for including rigorous patient-reported outcomes in clinical trials, and reflect on Dr Calvert’s recent JAMA paper on related ethical implications.

Related Content:

Ethical Considerations for the Inclusion of Patient-Reported Outcomes in Clinical Research

May 3, 2022

Lumbar spinal stenosis is a common cause of low back pain and disability in older people. Both nonoperative and operative therapies can improve symptoms from spinal stenosis. In this podcast, Jeffrey Katz, MD, MSc, from Harvard Medical School joins JAMA Deputy Editor Mary M. McDermott, MD, to discuss current evidence regarding diagnosis and optimal treatment of lumbar spinal stenosis, including when to consider invasive therapies for patients with symptoms of lumbar spinal stenosis.

Related Content:

Diagnosis and Management of Lumbar Spinal Stenosis

May 3, 2022

JAMA Associate Editor Linda Brubaker, MD, MS, from University of California San Diego, discusses the implications of self-monitoring of blood pressure in higher-risk pregnancies with Richard J. McManus, MBBS, PhD, from University of Oxford, UK, and Lucy C. Chappell, MB BChir, PhD, from King's College London.

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Apr 19, 2022

After certain adverse pregnancy outcomes, an individual’s risk for cardiovascular and other diseases increases. JAMA Associate Editor Linda Brubaker, MD, discusses these complications as indicators of future health problems, who is at risk, and what can be done to improve health for at-risk individuals and populations with Lynn M. Yee, MD, MPH, and JAMA Senior Editor Philip Greenland, MD, from Northwestern University, and Eliza C. Miller, MD, MS, from Columbia University.

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Apr 12, 2022

Pulmonary arterial hypertension is a rare condition that requires a thorough workup to evaluate for potential causes and right heart catheterization for definitive diagnosis and decision-making about treatment options. JAMA Associate Editor Kristin Walter, MD, MS, discusses the recent JAMA review article titled “Pulmonary Arterial Hypertension Classification, Diagnosis, and Treatment” with one of the authors, Nicole Ruopp, MD, assistant professor of medicine at Tufts Medical Center and Tufts University School of Medicine.

Related Content:

Diagnosis and Treatment of Pulmonary Arterial Hypertension

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