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JAMA Clinical Reviews

Interviews with expert clinicians and researchers about topics relevant to clinical practice and patient care, including updates in management of common conditions from JAMA, the Journal of the American Medical Association.
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Now displaying: March, 2021

In-depth interviews about current ideas and innovation in medicine, science, and clinical practice.

Mar 23, 2021

Semaglutide has recently been shown to induce clinically significant weight loss in patients with obesity that is sustained for as long as the drug is given. Tom Wadden, PhD, from the University of Pennsylvania, discusses results from the series of recent STEP trials and how they compare to the effects of other medications used to treat obesity.

Related Articles:

Effect of Subcutaneous Semaglutide vs Placebo as an Adjunct to Intensive Behavioral Therapy on Body Weight in Adults With Overweight or Obesity

Effect of Continued Weekly Subcutaneous Semaglutide vs Placebo on Weight Loss Maintenance in Adults With Overweight or Obesity

Authors have declared conflicts of interest related to the article discussed in this podcast. Visit the article on jama.com for the complete disclosure.

Mar 9, 2021

Performing repeated statistical comparisons on data can result in false-positive findings. Jing Cao, PhD, associate professor of statistics at Southern Methodist University, explains problems that can arise from multiple testing procedures and how to avoid making false conclusions.

Related Article:

Multiple Comparison Procedures

Mar 2, 2021

Irritable bowel syndrome (IBS) is a clinical syndrome of vague abdominal pain and cramping associated with diarrhea or constipation. IBS is a diagnosis of exclusion, and a variety of treatments can improve its symptoms. Michael Camilleri, MD, professor of medicine at the Mayo Clinic, discusses recent advances in the diagnosis and management of IBS.

Related Content:

Diagnosis and Treatment of Irritable Bowel Syndrome

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