Peripheral neuropathy is a highly prevalent and morbid condition affecting 2% to 7% of the population. Patients frequently experience pain and are at risk of falls, ulcerations, and amputations. It is most commonly occurs in patients with diabetes. For most cases, the diagnosis and treatment of neuropathy can be made without complex testing or referral to specialists. Drs. Eva Feldman and Brian Callaghan from the University of Michigan Department of Neurology, authors of Distal Symmetric Polyneuropathy and Electrodiagnostic Tests in Polyneuropathy and Radiculopathy, explain how to manage neuropathy.

Constipation is one of the most frequent problems clinicians are asked to deal with. Despite how common it is, constipation is frequently not treated adequately. In this podcast, Arnold Wald, MD, explains a stepwise approach to the management of constipation ranging from very simple measures to the most novel and complicated new medical therapies.

Articles discussed in this episode:

• JAMA Clinical Review: Constipation: Advances in Diagnosis and Treatment
• JAMA Clinical Guidelines Synopsis: Evaluation and Treatment of Patients With Constipation
• From The Medical Letter on Drugs and Therapeutics: Naloxegol (Movantik) for Opioid-Induced Constipation
• JAMA Patient Page: Constipation