Heart failure (HF) affects more than 64 million individuals worldwide, and 20% to 30% of patients with HF and systolic dysfunction have cardiac dyssynchrony due to conduction system disease. JAMA Review author Mihail Chelu, MD, PhD, of Baylor College of Medicine discusses cardiac resynchronization therapy with JAMA Associate Editor David Simel, MD, MHS.

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• Cardiac Resynchronization Therapy
• Leadless Ultrasound-Based Cardiac Resynchronization System in Heart Failure

In the US, approximately 66% of reproductive-aged women have at least 1 modifiable risk factor for adverse pregnancy outcomes. Authors and ob-gyns Kylie Cooper, MD, and Daniel Breitkopf, MD, both from the Mayo Clinic, discuss ways to reduce maternal morbidity and mortality and improve neonatal outcomes with JAMA Senior Editor Karen Lasser, MD, MPH.

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• Prepregnancy Care and Counseling

Endometrial cancer accounts for 95% of uterine cancers, which are the fourth most common cancer in women in the US. Author Karen McLean, MD, PhD, of Roswell Park Comprehensive Cancer Center joins JAMA Senior Editor Karen Lasser, MD, MPH, to discuss the current evidence about diagnosis and treatment of endometrial cancer.

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• Endometrial Cancer

Explore evidence-based clinical signs, diagnostic accuracy, and practical assessment strategies to optimize care with an in-depth look at the latest information on pediatric concussion. JAMA Review author Sonal N. Shah, MD, MPH, of Boston Children’s Hospital, discusses this and more with JAMA Associate Editor David Simel, MD, MHS.

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• Does This Child Have a Concussion?
• Even Mild Concussions Tied to Worse Cognition Later in Life
• Vestibular/Ocular Motor Screening (VOMS) in Suspected Concussion
• Balance and Gait Assessment Including Modified BESS
• Cervical Spine Examination in Suspected Concussion