Hepatitis B virus (HBV) infection affects around 254 million people worldwide and causes more than 1 million deaths annually. Author Anna Lok, MD, from the University of Michigan discusses HBV transmission, screening, and treatment with JAMA Associate Editor Beverly Forsyth, MD.
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Heart failure (HF) affects more than 64 million individuals worldwide, and 20% to 30% of patients with HF and systolic dysfunction have cardiac dyssynchrony due to conduction system disease. JAMA Review author Mihail Chelu, MD, PhD, of Baylor College of Medicine discusses cardiac resynchronization therapy with JAMA Associate Editor David Simel, MD, MHS.
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In the US, approximately 66% of reproductive-aged women have at least 1 modifiable risk factor for adverse pregnancy outcomes. Authors and ob-gyns Kylie Cooper, MD, and Daniel Breitkopf, MD, both from the Mayo Clinic, discuss ways to reduce maternal morbidity and mortality and improve neonatal outcomes with JAMA Senior Editor Karen Lasser, MD, MPH.
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Endometrial cancer accounts for 95% of uterine cancers, which are the fourth most common cancer in women in the US. Author Karen McLean, MD, PhD, of Roswell Park Comprehensive Cancer Center joins JAMA Senior Editor Karen Lasser, MD, MPH, to discuss the current evidence about diagnosis and treatment of endometrial cancer.
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Explore evidence-based clinical signs, diagnostic accuracy, and practical assessment strategies to optimize care with an in-depth look at the latest information on pediatric concussion. JAMA Review author Sonal N. Shah, MD, MPH, of Boston Children’s Hospital, discusses this and more with JAMA Associate Editor David Simel, MD, MHS.
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Absolute iron deficiency with or without anemia affects about 2 billion people worldwide and 14% of adults in the US. Discover causes, diagnosis, and best practices for oral and intravenous iron therapy in adults in this discussion between Michael Auerbach, MD, from Georgetown University School of Medicine, and JAMA Associate Editor Margaret Wheeler, MD.
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Interview with Thomas Ibounig, MD, author of Incidental Rotator Cuff Abnormalities on Magnetic Resonance Imaging and Brian T. Feeley, MD, author of Magnetic Resonance Imaging Abnormalities and Incidental Age-Related Changes. Hosted by Eve Rittenberg, MD.
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Resistant hypertension affects about 10% of those treated for hypertension. Managing it involves lowering sodium intake, exercising, losing weight, reducing alcohol consumption, and using optimal diuretics, combination pills, and mineralocorticoid antagonists. Author Michel Azizi, MD, PhD, from Hospital European Georges Pompidou in France discusses this and more with JAMA Associate Editor David L. Simel, MD, MHS.
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Peanut allergy affects about 2% of people in the US and most commonly develops in early childhood. Peanut introduction during infancy has led to decreased prevalence of peanut allergy. Author Elissa Abrams, MD, MPH, of the University of Manitoba joins JAMA Deputy Editor Kristin Walter, MD, MS, to discuss the clinical presentation and methods to diagnose, treat, and decrease the risk of peanut allergy.
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Overweight and obesity may cause 10% of new cancer diagnoses annually in the US. In this JAMA Review in the Translational Science series, author Neil Iyengar, MD, of Emory University discusses the biological pathways that may promote cancer in people with overweight or obesity and potential therapies with JAMA Deputy Editor Mary McDermott, MD.
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Chronic noninfectious diarrhea affects approximately 6% to 7% of adults in the US and significantly impairs quality of life. Author William Chey, MD, of the University of Michigan joins JAMA Deputy Editor Mary M. McDermott, MD, to discuss strategies for diagnosis and treatment of chronic, noninfectious diarrhea.
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Accurate assessment of intravascular volume facilitates decisions about fluid management in patients with volume overload. Author Edmund A. Liles Jr, MD, of the University of Utah joins JAMA Associate Editor David Simel, MD, MHS, to discuss best evidence from physical exam findings including ultrasound, radiographs, and lab studies for determining volume overload in spontaneously breathing patients.
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Type 1 diabetes affects approximately 2 million people in the US and 8.4 million people worldwide. Author Desmond Schatz, MD, of the University of Florida joins JAMA Deputy Editor Mary M. McDermott, MD, to discuss current evidence regarding diagnosis and treatment of type 1 diabetes.
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Mark Cuban, entrepreneur, investor, and cofounder of the Mark Cuban Cost Plus Drug Company, joins JAMA Editor in Chief Kirsten Bibbins-Domingo, PhD, MD, MAS, to discuss the role of pharmacy benefit managers, insurance formularies, and opaque pricing practices that shape how most Americans access prescription drugs. Hear why he thinks doctors are the good guys in a broken system.
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Opioid use disorder is the third most prevalent substance use disorder worldwide. Author Alexander Walley, MB, MSc, of Boston Medical Center and Boston University joins JAMA Deputy Editor Kristin Walter, MD, MS, to discuss the efficacy, safety, and practical considerations of treating patients with medications for opioid use disorder, opioid withdrawal, and opioid overdose.
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Ovarian cancer may be prevented with removal of the fallopian tubes during pelvic or select abdominal surgery in eligible women. This procedure, opportunistic salpingectomy, can be offered to more eligible women. Author Jurgen M. Piek, MD, PhD, of the Catharina Cancer Institute discusses this and more with JAMA Deputy Editor Linda Brubaker, MD, MS.
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IgA nephropathy is a chronic kidney disease involving deposition of IgA-containing immune complexes in the glomerulus, which often causes kidney failure within 10 to 20 years. Author Michelle Marie O'Shaughnessy, MB, BCh, BAO, MS, of Galway University joins JAMA Deputy Editor Kristin Walter, MD, MS, to discuss the symptoms, risk factors, diagnosis, treatment, and prognosis of IgA nephropathy in adults.
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Restless legs syndrome is a sleep-related neurologic disorder that causes an overwhelming urge to move the limbs, which can cause substantial sleep disturbance. Author John W. Winkelman, MD, PhD, of Harvard Medical School joins JAMA Deputy Editor Kristin Walter, MD, MS, to discuss the symptoms, risk factors, diagnosis, and treatment of restless legs syndrome.
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Mifepristone used with misoprostol is the most common abortion regimen in the US. It is also a focal point of reproductive health policy and politics, with controversy over its legal status and regulation by the US Food and Drug Administration (FDA). Author G. Caleb Alexander, MD, MS, from Johns Hopkins discusses this and more with JAMA Deputy Editor Joseph S. Ross, MD, MHS.
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Incidence rates of gastric cancer in younger individuals are on the rise and gastric cancer is the fifth-leading cause of cancer-related deaths worldwide. JAMA Review author Haeseong Park, MD, MPH, from the Dana Farber Cancer Institute, discusses this and more with JAMA Senior Editor Karen Lasser, MD, MPH.
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